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Related Experiment Videos

Auditory brain-stem responses in brain death.

A Starr

    Brain : a Journal of Neurology
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Auditory brain-stem responses in brain death patients were absent or showed only Wave I. This objective measure helps evaluate brain-stem function in suspected brain death cases.

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    Area of Science:

    • Neuroscience
    • Clinical Neurology

    Background:

    • Brain death diagnosis requires confirmation of irreversible cessation of all brain functions.
    • Auditory brain-stem responses (ABRs) assess the integrity of the auditory pathway through the brain-stem.

    Observation:

    • In 27 brain-dead patients, ABRs were absent or showed only Wave I.
    • Wave I, when present, had normal amplitude but prolonged latency.
    • Longitudinal study of four patients showed progressive ABR deterioration to Wave I alone as brain death ensued.

    Findings:

    • ABRs provide an objective electrophysiological measure of brain-stem function.
    • The pattern of ABR changes, particularly the loss of later waves and Wave I latency prolongation, correlates with brain death.

    Implications:

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    • ABRs can serve as a valuable tool in the objective assessment of brain death.
    • This technique aids in confirming the irreversible loss of brain-stem function.