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Related Experiment Videos

Microbial flora of the normal esophagus.

D Gagliardi1, S Makihara, P R Corsi

  • 1Surgical Department, Santa Cara Medical School of São Paulo, Brazil.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
|March 11, 1999
PubMed
Summary

This study investigated normal esophageal flora in 30 patients, finding a high isolation frequency of mixed microorganisms. Streptococcus viridans was the most common germ identified, suggesting a link between oropharyngeal and esophageal flora.

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Area of Science:

  • Microbiology
  • Gastroenterology

Background:

  • The endogenous flora of skin and mucous membranes is documented.
  • Normal esophageal flora has not been well-described in existing literature.
  • Understanding esophageal flora is crucial for therapeutic applications.

Purpose of the Study:

  • To determine the normal esophageal flora.
  • To investigate the correlation between oropharyngeal and esophageal flora.
  • To establish baseline data for potential clinical relevance.

Main Methods:

  • Collected esophageal and oropharyngeal samples from 30 patients undergoing upper digestive tract endoscopy.
  • Utilized a saline lavage method (10 ml 0.9% physiological solution) for sample collection.
  • Identified microorganisms using standard microbiological techniques.

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Main Results:

  • A high frequency of germ isolation was observed in esophageal samples.
  • Mixed microbial flora was identified in the esophagus.
  • Streptococcus viridans was the most frequently isolated microorganism.

Conclusions:

  • The employed method demonstrated a high isolation rate for esophageal microorganisms.
  • Streptococcus viridans is a predominant component of normal esophageal flora.
  • A potential correlation exists between oropharyngeal and esophageal microbial communities.