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Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

[Human immunodeficiency virus (HIV) infection. The effectiveness of different diagnostic sequences in suspected

A Cortés Blanco¹, C Sáez Lavilla, R Martínez Lázaro

¹Servicio de Medicina Nuclear, Hospital Miguel Servet, Zaragoza.

Anales De Medicina Interna (Madrid, Spain : 1984)

|March 25, 1999

Abstract

Background:

Assessment of different diagnostic sequences, in patients VIH(+) with a suspected pulmonary infection.

Methods:

A cross-sectional descriptive study of 76 HIV(+) patients with suspected respiratory infection. It has been determined the validity and the pretest and post-test probability of the radiology (Rx) of thorax, 67Ga pulmonary scintigraphy and seric LDH levels, in order to design four different diagnostic algorithms.

Results:

The diagnostic sequence Rx-LDH-scintigraphy with normal results involved an infection probability of 58.0%. Pathological Rx with successively normal LDH and scintigraphy, implied a likelihood of 97.0%. The LDH elevation in sequence with scintigraphy and Rx rose to 96.1% if both were abnormal and diminished to 8.3% if normal.

Conclusions:

The LDH elevation associated with the sequence of normal Rx and scintigraphy suggests a low infection likelihood. On the contrary, associated with pathological Rx and scintigraphy in sequence, practically assures the pulmonary infection.

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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment

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