Related Experiment Video

Updated: Aug 18, 2026

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells
11:16

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells

Published on: February 15, 2019

Management of a measles outbreak among Old World nonhuman primates

M E Willy1, R A Woodward, V B Thornton

  • 1Hospital Epidemiology Service, Warren G. Magnuson Clinical Center, Bethesda, Maryland, USA.

Laboratory Animal Science
|March 25, 1999
PubMed
Abstract

Insights

A 1996 measles outbreak in nonhuman primates highlighted the need for a control plan. Preventive vaccination for both humans and primates is crucial to prevent facility-wide outbreaks of this infectious disease.

Area of Science:

  • Veterinary Epidemiology
  • Infectious Disease Control
  • Primate Health

Background:

  • A measles outbreak occurred in a facility housing Old World nonhuman primates in 1996.
  • The outbreak provided a unique opportunity to study measles epidemiology in an animal-handling environment.

Purpose of the Study:

  • To investigate the epidemiology of a measles outbreak in nonhuman primates.
  • To understand disease transmission in an animal-handling setting.

Main Methods:

  • Collected serum and urine specimens from infected monkeys, those with suspicious signs, and employees.
  • Tested serum for measles virus-specific IgG and IgM antibodies.
  • Tested urine for measles virus using virus isolation or RT-PCR.

Main Results:

  • 94 monkeys across two facilities showed evidence of acute measles infection.
  • The outbreak was linked to a wild-type measles virus associated with recent human cases.
  • Quarantine and mass vaccination were effective in controlling the spread.

Conclusions:

  • Highlights the importance of a comprehensive measles control plan.
  • Recommends preventive vaccination programs for both humans and nonhuman primates.
  • Emphasizes reducing the risk of facility-wide outbreaks.

More Related Videos

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies04:10

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Hand-Rearing Method for Infant Marmosets04:52

Hand-Rearing Method for Infant Marmosets

Published on: June 9, 2023

Related Concept Videos

Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...