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[HIV-1 subtypes in Russia in 1987-1988]
A F Bobkov1, E V Kazennova, L M Selimova
1Ivanovsky Research Institute of Virology, Russian Research and Methodological Center for Prophylaxis and Control of AIDS, Moscow, Russia.
Abstract:
The subtyping of 350 isolates of HIV-1, isolated on the territories of 38 subjects of the Russian Federation, was carried out. The analysis was made by the method of the comparative heteroduplex mobility assay, as well as by the determination of the sequence of genes env [correction of ens] (gp 120) and gag (p17-p24). The study revealed that more than 50% of all cases of HIV-1 infection were caused by closely related variants of subtype A virus. The number of cases of HIV-1 infection caused by recombinant virus A/B was not less than 25%. The total number of cases caused by viruses of subtypes C, D, E, F and H was not more than 5%.