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Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network
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[MICROBIOCENOSIS, IMMUNE SYSTEM AND HEREDITY].

D A Voevodin, G N Rozanova, A V Poddubikov

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    |January 30, 2019
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    Summary
    This summary is machine-generated.

    The interaction between prokaryotic and eukaryotic systems shapes phenotypes and health. This process, influenced by maternal factors and stress, may offer a mechanism for perinatal programming and correcting congenital conditions.

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    Area of Science:

    • Microbiology
    • Developmental Biology
    • Immunology

    Background:

    • Prokaryotic and eukaryotic systems interact to form phenotypes in plants, animals, and humans.
    • External environmental factors influence the development of adaptive capabilities, enhancing the biological status of prokaryotic structures for health.
    • The phenotype is shaped by micro-environmental factors, immunological tolerance, and maternal influences, particularly during the perinatal period.

    Purpose of the Study:

    • To explore the role of prokaryotic-eukaryotic interactions in phenotype formation and variability.
    • To investigate the potential of these interactions as a mechanism for perinatal programming and epigenetic inheritance.
    • To identify approaches for correcting chronic and congenital pathologies through modulation of these interactions.

    Main Methods:

    • Analysis of phenotype formation influenced by external environmental factors.
    • Evaluation of immunological programming and maternal influence in perinatal development.
    • Consideration of micro-variability resulting from external stress impacts.

    Main Results:

    • Prokaryotic-eukaryotic interactions are fundamental to phenotype development and health.
    • Maternal influence and external stress significantly impact micro-environmental interactions during the perinatal period.
    • These interactions represent a potential mechanism for perinatal programming and epigenetic inheritance.

    Conclusions:

    • Prokaryotic-eukaryotic interaction is a key mechanism in phenotype formation and health maintenance.
    • This interaction offers a potential pathway for correcting chronic and congenital diseases.
    • Improved monitoring and assessment methods for children's microbiocenosis are necessary.