[Cytoprotection of the endothelium cells in primary hypertension]

Normal endothelium cells play a huge role in small blood vessels function. It's not only physical barrier between blood and surrounding structures, but also producers a lot vasodilatators and vasodepresors. It's controlled by blood humoral factors plaing important role on blood circulation physiology. Endothelium cells injury gives its function abnormality local and general as well. The main injury factor is hypertension, which provides to endothelium disfunction with vasopressors level growth which induces hypertension. Also primary endothelial injury induces hypertension and atherogenesis.