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A description of a successful computerized adverse drug reaction tracking program
1University of Illinois Hospital Pharmacy, Chicago 60612.
Hospital Formulary
|April 1, 1990
Summary
A new database system improved adverse drug reaction (ADR) reporting at a hospital, increasing reports by over 400%. This system aids in identifying drug safety trends and enhancing patient care through better data analysis.
Area of Science:
- Pharmacovigilance
- Health Informatics
- Clinical Pharmacy
Background:
- The University of Illinois Hospital Drug Information Center previously lacked an efficient system for managing adverse drug reaction (ADR) data.
- Manual or less sophisticated methods hindered comprehensive analysis and trend identification.
Purpose of the Study:
- To evaluate the implementation and impact of a new database software program for storing and retrieving reported adverse drug reactions (ADRs).
- To assess the system's features and its effect on the volume and analysis of ADR data.
Main Methods:
- Implementation of File Express (Version 4.0) database software for ADR reporting and data management.
- Analysis of ADR report numbers before and after software implementation, correlating with educational efforts and revised reporting procedures.
- Retrospective analysis of ADR reports to identify trends based on drug and route of administration.
Main Results:
- A significant increase in reported ADRs, from 24 in 1987 to 124 in 1988, was observed.
- Pharmacists emerged as the primary reporters of ADRs within the system.
- The database facilitated easier report generation, data sorting, and large-scale data storage.
Conclusions:
- The computer-based ADR reporting system, enhanced by user-friendly software, demonstrably improved data collection and reporting efficiency.
- Sharing information from this system can help identify ADR trends, potentially leading to a decrease in ADR incidence and improved patient safety.
- Pharmacovigilance efforts can be significantly bolstered by adopting such informatics solutions.
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