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Updated: Aug 5, 2026

High-Resolution Respirometry to Assess Bioenergetics in Cells and Tissues Using Chamber- and Plate-Based Respirometers
Published on: October 26, 2021
Abstract:
It is proposed that the earliest cellular organisms relied upon a novel type of energy transduction termed palirrhotrophy, which generates a high-energy "currency" chemiosmotically by exploiting the rhythmic variations in salinity which occur in the estuarine environment. Calculations based on estimates of contemporary chemiosmotic transduction efficiency suggest that such a mechanism could produce usable energy in high yield. The minimum polypeptide requirement for palirrhotrophy compares favorably with that of a fermentative pathway. It is suggested that palirrhotrophic organisms exist today but are difficult to detect.
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