Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Specific immunotherapy].

J Just1, A Houzel-Charavel, A Grimfeld

  • 1Polyclinique de pneumologie pédiatrique, hôpital d'Enfants Armand-Trousseau, Paris, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 7, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mild liver dysfunction in Klinefelter syndrome is associated with abdominal obesity and elevated lipids but not testosterone treatment.

Journal of endocrinological investigation·2024
Same author

Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis.

Allergy·2023
Same author

Persistent influence of precession on northern ice sheet variability since the early Pleistocene.

Science (New York, N.Y.)·2022
Same author

Publisher Correction: Indo-Pacific Walker circulation drove Pleistocene African aridification.

Nature·2022
Same author

Indo-Pacific Walker circulation drove Pleistocene African aridification.

Nature·2021
Same author

A melt-electrowritten filter for capture and culture of circulating colon cancer cells.

Materials today. Bio·2020
Same journal

Family experiences of paediatric palliative care during hospital-at-home: a systematic review.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Knowledge of maternity caregivers on vaccination BCG recommendations and circuits.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

"CRANIOQUALITY study: Quality of life in children with non-syndromic craniosynostosis after surgery".

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Chronological evolution of brain imaging of hemiconvulsion-hemiplegia-epilepsy from 5 cases in Mayotte island.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Point-of-care capillary blood ketone testing to predict the need for intravenous or nasogastric tube rehydration in children with acute gastroenteritis.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Transition practices of patients with inflammatory bowel disease from pediatric to adult healthcare systems. Results from a national survey.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
See all related articles

Specific immunotherapy (SIT) offers a potential cure for allergies by rebalancing immune responses. Early intervention in childhood asthma may alter the disease

Area of Science:

  • Immunology and Allergy Research
  • Environmental Health Science

Background:

  • Rising allergy prevalence linked to environmental changes.
  • Specific immunotherapy (SIT) is the only etiological treatment for allergic diseases.
  • SIT may alter the natural history of respiratory allergies if initiated early in life.

Purpose of the Study:

  • To explore the potential of SIT in managing allergic diseases.
  • To investigate the immunological mechanisms underlying SIT.
  • To define optimal patient selection and treatment protocols for SIT.

Main Methods:

  • Review of experimental studies on SIT mechanisms.
  • Analysis of clinical trial data for subcutaneous SIT efficacy.
  • Consideration of recombinant allergen technology for improved immunomodulation.

Related Experiment Videos

Main Results:

  • SIT may restore the Th1/Th2 cell balance disrupted in allergies.
  • Subcutaneous SIT is an effective route for allergens like grass pollens, house dust, and mites.
  • Early SIT initiation in childhood asthma can prevent airway remodeling.

Conclusions:

  • Careful patient selection is crucial for successful SIT.
  • Subcutaneous SIT, when administered rigorously, is safe and effective.
  • Recombinant allergens offer promise for enhanced SIT efficacy and tolerability.