Related Experiment Videos
[Vaccination against type 1 diabetes at the clinical trial stage]
1University of Washington, Seattle, USA. ake@u.washington.edu
Lakartidningen
|April 9, 1999
Abstract:
The occurrence of type I diabetes is associated with autoimmunity against insulin, glutamate decarboxylase (GAD65) and the transmembrane protein IA-2. Experiments in the spontaneously diabetic NOD mouse and the BB rat have shown early autoantigen treatment to confer protection from diabetes. The question remains of whether human type I diabetes can be prevented by autoantigen 'vaccination'.