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Updated: Sep 24, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
[Liver changes in people of conscription age--"carriers" of hepatitis B and C viruses]
S A Povzun1, V S Chirskiĭ, K V Zhdanov
1Military Medical Academy, St. Petersburg.
Abstract:
89 liver needle biopsies from young persons--HBV and HCV carriers--were studied histologically, immunohistochemically, morphometrically and electron microscopically. Groups with compensatory-adaptive and degenerative liver lesions, those with mild manifestations of a chronic virus infection, and those with chronic hepatitis of minimal and weak activity were identified. Latent chronic hepatitis is found in 68.5% of HBV and HCV carriers. Morphological picture of HCV infection is more pronounced as compared to that of HBV infection. The role of eosinophils in the development of hepatitis B and C forms lacking clinical symptoms is demonstrated.
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