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Related Concept Videos

ATP Driven Pumps II: P-type Pumps01:34

ATP Driven Pumps II: P-type Pumps

The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
ATP Driven Pumps III: V-type Pumps01:30

ATP Driven Pumps III: V-type Pumps

V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
Assessment of the Cardiovascular System III: Palpation01:27

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Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...

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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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Published on: June 12, 2021

Effectiveness of the A-V impulse hand pump.

M Ramesh1, B Morrissey, J B Healy

  • 1Sligo General Hospital, Ireland.

The Journal of Bone and Joint Surgery. British Volume
|April 16, 1999
PubMed
Summary

A pneumatic compression device effectively reduced acute hand swelling and pain, improving function after trauma or surgery. This innovative hand pump offers a significant reduction in swelling, leading to faster recovery and near-normal hand function upon hospital discharge.

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Area of Science:

  • Orthopedics
  • Vascular Surgery
  • Rehabilitation Medicine

Background:

  • Acute hand swelling is a frequent complication post-trauma or surgery.
  • Swelling leads to significant pain and functional deficits.
  • Effective management strategies for hand edema are crucial.

Purpose of the Study:

  • To evaluate the efficacy of a pneumatic compression device (A-V impulse hand pump) in managing acute hand swelling.
  • To assess the impact of the device on venous return, pain, and hand function.
  • To determine optimal usage protocols for the pneumatic hand pump.

Main Methods:

  • Prospective study involving 47 patients with acute hand swelling.
  • Utilized a pneumatic compression device (A-V impulse hand pump).
  • Assessed swelling reduction, venous return velocity (Duplex scan of median cubital vein), pain levels, and hand function.

Main Results:

  • Continuous 48-hour use reduced swelling by 78.6% compared to the uninjured hand.
  • Intermittent use (12 hours/24 hours) also showed statistically significant swelling reduction.
  • Reported subjective pain reduction and objective functional improvement.
  • Patients achieved near-normal hand function by hospital discharge (average 48 hours).

Conclusions:

  • The A-V impulse hand pump is an effective treatment for acute hand swelling.
  • The device enhances venous return, alleviates pain, and restores hand function.
  • Pneumatic compression offers a promising therapeutic option for post-traumatic and post-surgical hand edema.