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[Spinal cord stimulation in angina pectoris--what is the current situation?]
H Norrsell1, T Eliasson, L E Augustinsson
1Multidisciplinärt smärtcentrum, medicinska kliniken, Sahlgrenska Universitetssjukhuset/Ostra. henrik.norrsell@invmed.gu-se
Summary
Spinal cord stimulation effectively treats intractable angina pectoris, offering anti-anginal and anti-ischaemic effects. Recent studies show it rivals coronary artery bypass surgery in symptom relief, though mechanisms require further investigation.
Area of Science:
- Cardiology
- Neuromodulation
- Pain Management
Background:
- Spinal cord stimulation (SCS) has been a therapeutic option for intractable angina pectoris since 1985.
- Studies indicate SCS provides both anti-anginal and anti-ischaemic benefits.
- The precise mechanisms of action for SCS in angina remain incompletely understood.
Purpose of the Study:
- To review current trends and findings in the use of spinal cord stimulation for angina pectoris.
- To evaluate the efficacy of SCS in comparison to established surgical interventions.
- To highlight areas of ongoing research regarding SCS mechanisms.
Main Methods:
- Review of existing literature on spinal cord stimulation for angina.
- Analysis of findings from randomized prospective studies comparing SCS to coronary artery bypass surgery.
- Examination of investigations into the underlying mechanisms of SCS effects.
Main Results:
- Spinal cord stimulation demonstrates good results in treating intractable angina pectoris.
- Both anti-anginal and anti-ischaemic effects have been documented.
- A randomized study found SCS comparable to coronary artery bypass surgery in providing symptom relief.
Conclusions:
- Spinal cord stimulation is a viable treatment for refractory angina pectoris.
- Further research is needed to elucidate the exact mechanisms of SCS.
- SCS presents a valuable alternative or adjunct therapy in cardiovascular symptom management.