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The Resource Mothers Program for Maternal Phenylketonuria
P S St James1, E Shapiro, S E Waisbren
1Psychology Department, University of Massachusetts at Boston, USA.
Objectives:
The purpose of this study was to measure the effectiveness of resource mothers in reducing adverse consequences of maternal phenylketonuria.
Methods:
Nineteen pregnancies in the resource mothers group were compared with 64 pregnancies in phenylketonuric women without resource mothers. Weeks to metabolic control and offspring outcome were measured.
Results:
Mean number of weeks to metabolic control was 8.5 (SE = 2.2) in the resource mothers group, as compared with 16.1 (SE = 1.7) in the comparison group. Infants of women in the resource mothers group had larger birth head circumferences and higher developmental quotients.
Conclusions:
The resource mothers program described here improves metabolic control in pregnant women with phenylketonuria.