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Published on: April 14, 2014
[Devic's optic neuromyelitis: analysis of 7 cases]
F Sebastián de la Cruz1, E López-Dolado
1Sección de Neurología, Hospital Nacional de Parapléjicos, Toledo, España.
Revista De Neurologia
|May 7, 1999
Summary
Devic's optic neuromyelitis is a rare, relapsing condition causing optic neuritis and myelitis, often leading to severe disability. Early diagnosis and treatment are crucial for managing this challenging neurological disorder.
Area of Science:
- Neurology
- Neuroimmunology
- Ophthalmology
Background:
- Devic's optic neuromyelitis is a rare autoimmune disorder.
- It involves inflammation of the optic nerves and spinal cord.
- The condition typically has a poor prognosis, leading to significant disability.
Observation:
- Seven cases of Devic's optic neuromyelitis were studied.
- Clinical and neuroimaging features, CSF analysis, and complications were evaluated.
- Data was compared with existing literature.
Findings:
- Devic's optic neuromyelitis is rare, accounting for ~0.1% of spinal cord inflammatory pathology.
- Clinical and imaging findings may initially mismatch, necessitating repeat investigations for diagnosis.
- Differential diagnosis includes intramedullary tumors and psychiatric disorders.
Implications:
- The condition often leads to severe visual loss and spinal cord lesions, resulting in profound disability.
- Accurate diagnosis relies on clinical, imaging, and biochemical criteria.
- Definitive diagnosis may require post-mortem examination.
