[Relationship between blocking the erythrocyte surface and the quantity of IgG molecules bound in the process of...

Under different conditions of the IgG-sensitization of the tannin-treated erythrocytes a determination was made of the degree of blocking the cell surface. There was shown a reverse relationship between the amount of the bound IgG molecules and their portions bound by the surface with the maximal cross-section. Fixation of the IgG by means of CH2O at the end of sensitization led to the additional blocking of the erythrocyte surface. The limit of the erythrocyte saturation with the IgG molecules was controlled by the greatest possible density of the globulin molecules localization.