[Diffuse polyposis of the large intestine complicated by amyloidosis of the internal organs]

Polyposis of the large intestine is a common affliction of the intestine which usually occurs as a result of inflammatory diseases or of dysplasia of embryonic anlages. Malignization of diffuse polyposis is observed in 70-100% of cases. A case of diffuse polyposis of the large intestine with initial phenomena of malignization in a male patient aged 44 years is described. The case in question was characterized by the presence of accompanying diffuse amyloidosis of a number of internal organs (kidney, spleen, pancreas). The onset of amyloidosis in this case was associated apparently with the character of absorption by a pathologically changed surface of the large intestine mucosa and with the enlargement of the surface of absorption of products of the protein metabolism.