[Changes in lysosomal enzymatic activity during the limited feeding and physical loading of white rats]

The effect of deficient alimentation and physical exertion on the total and free activity of two lysosome enzymes: acid phosphatase and beta-N-acetylglucose aminidase, in liver homogenate, and in serum--for the latter enzyme, is investigated in a series of 63 white rats at two different durations of the experiment (20 and 140 days). An increase of the free activity of both enzymes is recorded in the groups subjected to a limited nutrition, an increase which is interpreted as an expression of enhanced permeability of the lysosome membrane during the transition to partial andogenous alimentation. The applied physical loading failed to produce additional changes in the activity of the lysosome enzymes under study.