[Portosystemic encephalopathy and splanchnic hemodynamics in liver cirrhosis]

In 166 patients with liver cirrhosis (LC) and the portal hypertension syndrome the complex hemodynamical investigations were performed. It was established that portosystemic encephalopathy (PSE) is caused by the portosystemic shunts occurrence resulting in lowering of the volumetric blood flow in portal vein and hepatic artery, the diameter and intraluminal pressure in portal vein are diminished. It was observed in patients with encephalopathy, comparing with healthy persons, the hyperdynamical state of splenic blood circulation with the volumetric blood flow enhancement in a. et v. lienalis, and in patients with LC, suffering PSE, the volumetric blood flow in a. et v. lienalis is less than in patients without encephalopathy. While encephalopathy there was observed the enhancement of volumetric component of arterial blood and the lowering of the blood component from v. portae in common hepatic blood flow, including the liver inflow level and the sinusoid vessels level.