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Updated: Jul 22, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Biological considerations with pelvic neoplasms
1Division of Surgical Oncology, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA.
Abstract:
The strategy of therapy for any neoplasm is determined to a significant degree by the biological characteristics of the neoplasm. The ones benefited most by surgical ablation are the cancers that grow locally but never metastasize. The second group is composed of neoplasms with exceedingly slow growth rates permitting long periods of symptom-free survival before recidivation. Many such cancers occur in pelvic structures requiring understanding of the nature of the cancers and then techniques necessary for their resection. The review provides an introduction to some of the relevant biological considerations.
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