Related Experiment Video
Updated: Aug 11, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
Published on: September 26, 2013
[The TH2 theory in allergy]
E Rojas Ramos1, N E Martínez Jiménez
1Médicos Adscritos al Servicio de Alergia e Inmunología Clínica, Hospital Regional 1o de Octubre, ISSSTE.
Abstract:
The allergic diseases are determined by genetics and thought to affect between 20 to 30 percent of general people in developed countries. The prevalence has increased in the last decade. The allergic diseases are characterised by an increase of B-lymphocytes' ability to produce IgE antibody; this synthesis of human IgE is a result of collaboration between subsets of T helper cells CD4+ and B cells. The functional property of Th cells has been studied recently, fundamentally Type 2, in the cooperation among IgE-producing B cells, mast cell, basophils and eosinophil in the allergic reaction. This concept is known as the Th2 theory in allergy.
Related Concept Videos
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Allergic Reactions
Allergic Drug Reactions
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

