Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prepubertal testicular teratomas.

D K Gupta1, R Kataria, M C Sharma

  • 1Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|July 31, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-Hodgkin lymphoma arising in a vallecular cyst: A rare clinical entity.

Medical journal, Armed Forces India·2026
Same author

Role of hyperbaric oxygen therapy in idiopathic sudden sensorineural hearing loss management: A multicentre experience.

Medical journal, Armed Forces India·2026
Same author

Eyelid myeloid sarcoma heralding relapse of acute myeloid leukemia in a child: First report from India and literature review.

Indian journal of cancer·2025
Same author

Significance of increased 18F-FDG uptake in determining pathological status in post-chemotherapy lymphoma cases involving head-neck region on PET-CT.

Medical journal, Armed Forces India·2025
Same author

Congenital and Acquired Choanal Atresia: A Comprehensive Case Series on the Diagnosis and Contemporary Management.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2025
Same author

Generation of field-reversed configurations via neutral beam injection.

Nature communications·2025
Same journal

European Paediatric Surgeons' Association Consensus Statement on the Management of Meconium Ileus.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same journal

Dynamic Compression System versus Self-Adjustable Bracing for Pectus Carinatum: Clinical Outcomes and Cost Comparison.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same journal

International Variation in Pediatric Gastrostomy Insertion Techniques and Perioperative Management: A Survey of Members of the European Pediatric Surgeons' Association.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same journal

Surgical versus Non-Surgical Management of High-Grade Pediatric Pancreatic Trauma: A National TQIP Analysis Stratified by Hemodynamic Stability.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same journal

Pneumatic Balloon Dilation versus Heller's Myotomy in Pediatric Achalasia: A Systematic Review and Meta-Analysis.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same journal

Bar-Related Infections After Minimally Invasive Repair of Pectus Excavatum: A 25-Year Single-Center Retrospective Cohort Study.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
See all related articles

Pediatric testicular teratomas are unique tumors. This study analyzed 5 cases, finding they differ from adult teratomas and require careful management, with most patients achieving good outcomes post-surgery.

Area of Science:

  • Pediatric Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Testicular teratomas in children present distinct pathological features and behavior compared to adult or other pediatric teratomas.
  • These tumors represent a significant portion of pediatric testicular neoplasms, necessitating specific diagnostic and management strategies.

Purpose of the Study:

  • To analyze the clinical presentation, pathological profile, and outcomes of prepubertal testicular teratomas.
  • To evaluate the role of serum markers and immunohistochemistry in diagnosis and management.
  • To assess the feasibility and outcomes of testicular-sparing surgery versus orchiectomy.

Main Methods:

  • Retrospective analysis of 5 prepubertal children diagnosed with testicular teratomas over 12 years.
  • Review of clinical data, including age at presentation, tumor laterality, and presenting symptoms.

Related Experiment Videos

  • Histopathological examination and immunohistochemical staining for Alpha-fetoprotein (AFP) and other markers.

    • Main Results:

    • Testicular teratomas constituted 25% of pediatric testicular tumors in the study cohort.
    • The mean age at presentation was 6.7 months, with right testis involvement in most cases.
    • Elevated serum AFP was observed in one case with immature teratoma; levels normalized post-orchiectomy.
    • Testicular-sparing surgery was attempted but ultimately orchiectomy was performed in all cases due to tumor extent or characteristics.

    Conclusions:

    • Prepubertal testicular teratomas exhibit unique characteristics requiring tailored management approaches.
    • While orchiectomy remains a common treatment, careful pathological assessment is crucial.
    • All patients demonstrated favorable outcomes with no evidence of recurrence after a mean follow-up of 4.7 years.