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[Conjunctival pseudolymphoma in infectious mononucleosis]
C W Spraul1, T Mattfeldt, G K Lang
1Universitäts-Augenklinik Ulm. christoph.spraul@medizin.uni-ulm.de
Klinische Monatsblatter Fur Augenheilkunde
|August 17, 1999
Summary
Epstein-Barr virus infection can cause a rare conjunctival tumor in young adults. This salmon-colored mass, associated with infectious mononucleosis, may spontaneously resolve.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Oncology
Background:
- Epstein-Barr virus (EBV) commonly causes infectious mononucleosis.
- Conjunctival manifestations of EBV are typically limited to follicular conjunctivitis.
Observation:
- A 19-year-old male presented with a unilateral, salmon-colored subconjunctival mass.
- Symptoms included sore throat, cervical lymphadenopathy, and laboratory evidence of EBV infection.
- Biopsy revealed a mixed inflammatory infiltrate.
Findings:
- The conjunctival mass showed spontaneous regression over 8 weeks.
- High titers of Epstein-Barr-Virus-IgG and -IgM confirmed infectious mononucleosis.
- Histopathology indicated a reactive inflammatory process rather than malignancy.
Implications:
- Conjunctival tumors in the context of infectious mononucleosis require careful evaluation.
- EBV-related conjunctival masses may mimic ocular lymphoma.
- Consider infectious mononucleosis in the differential diagnosis of atypical conjunctival lesions.