Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone localization.

L A Robinson1

  • 1Department of Surgery, University of South Florida College of Medicine, Tampa, USA. robinson@moffitt.usf.edu

Surgical Oncology Clinics of North America
|August 17, 1999
PubMed
Summary
This summary is machine-generated.

Accurate bone metastasis diagnosis is crucial for cancer staging. A new gamma probe allows precise, guided biopsy of suspected bone metastases, improving diagnostic accuracy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introducing the H2020 AQUACROSS project: Knowledge, Assessment, and Management for AQUAtic Biodiversity and Ecosystem Services aCROSS EU policies.

The Science of the total environment·2018
Same author

Identifying barriers, conflict and opportunity in managing aquatic ecosystems.

The Science of the total environment·2018
Same author

The use of gamification in the teaching of disease epidemics and pandemics.

FEMS microbiology letters·2018
Same author

Post-feeding activity of Lucilia sericata (Diptera: Calliphoridae) on common domestic indoor surfaces and its effect on development.

Forensic science international·2018
Same author

Normothermic Ex Vivo Kidney Perfusion Following Static Cold Storage-Brief, Intermediate, or Prolonged Perfusion for Optimal Renal Graft Reconditioning?

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
Same author

Continuous Normothermic Ex Vivo Kidney Perfusion Is Superior to Brief Normothermic Perfusion Following Static Cold Storage in Donation After Circulatory Death Pig Kidney Transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016
Same journal

Small Incisions, Big Impact-Robotic Surgery Is Revolutionizing Cancer Care.

Surgical oncology clinics of North America·2026
Same journal

Minimally Invasive and Robotic Surgery for Cancer.

Surgical oncology clinics of North America·2026
Same journal

TeleSurgery: The Present and the Future for Minimally Invasive and Robotic Surgery.

Surgical oncology clinics of North America·2026
Same journal

Minimally Invasive and Robotic Surgery for Rectal Cancer.

Surgical oncology clinics of North America·2026
Same journal

Minimally Invasive/Robotic Surgery for Colon Cancer.

Surgical oncology clinics of North America·2026
Same journal

Minimally Invasive Surgery in Liver Transplantation.

Surgical oncology clinics of North America·2026
See all related articles

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Surgical Pathology

Background:

  • Accurate staging of malignancies is essential for effective cancer treatment planning.
  • Radionuclide bone scans can suggest bone metastases, but histological confirmation is necessary due to false positives.
  • Biopsying subtle bone scan abnormalities without clear radiographic or symptomatic localization is challenging.

Purpose of the Study:

  • To evaluate the utility of a hand-held gamma probe for radioisotope-guided open biopsy in cases of suspected bone metastases.
  • To assess the accuracy and sensitivity of this technique in identifying metastatic bone lesions.

Main Methods:

  • Utilized a recently described intraoperative hand-held gamma probe for radioisotope-guided open biopsy.
  • Focused on clinically suspected bone metastases where conventional imaging was inconclusive or normal.

Related Experiment Videos

  • Performed open biopsies guided by the gamma probe to target areas of radiotracer uptake.

    • Main Results:

    • The hand-held gamma probe demonstrated high accuracy and sensitivity in guiding open biopsies.
    • Radioisotope-guided biopsy facilitated precise tissue sampling of suspected bone metastases.
    • This method overcomes the difficulties associated with biopsying non-localized or subtle bone scan abnormalities.

    Conclusions:

    • Intraoperative use of a hand-held gamma probe is an accurate and sensitive method for radioisotope-guided open biopsy of suspected bone metastases.
    • This technique improves the diagnostic yield for bone metastases when conventional methods are insufficient.
    • Gamma probe-guided biopsy enhances the ability to obtain histological confirmation, crucial for accurate cancer staging and treatment selection.