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Cervical spine cord compression by eosinophilic granuloma. Case report
E B Duarte-Silva1, Noujaim J el-K, F Carnevale
1São Vicente de Paulo Hospital (HSVP) & Federal Fluminense University (UFF) Neurology Department, RJ, Brazil.
Arquivos De Neuro-Psiquiatria
|August 18, 1999
Summary
Eosinophilic granuloma, a form of Langerhans cell histiocytosis, rarely affects adults. This case highlights successful treatment of cervical spinal cord compression in a 42-year-old man.
Area of Science:
- Oncology
- Pathology
- Neurology
Background:
- Eosinophilic granuloma is the most common benign form of Langerhans cell histiocytosis.
- It typically affects children and adolescents, manifesting as localized bone lesions.
Observation:
- Vertebral involvement in Langerhans cell histiocytosis is uncommon (8%), with cervical spine involvement being rare.
- Cervical spinal cord and root compression are exceptionally rare, with only five prior cases reported.
Findings:
- This report details the sixth case of cervical spinal cord compression due to eosinophilic granuloma in a 42-year-old male.
- The patient experienced symptom resolution and remained asymptomatic post-treatment with surgery and low-dose radiation therapy.
Implications:
- This case underscores the potential for surgical intervention and radiation therapy in managing rare adult cases of eosinophilic granuloma with spinal cord compression.
- It contributes to the literature on clinical, radiological, and histological features, guiding future treatment strategies.