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Updated: Oct 19, 2026

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
[Asthma and covert toxocariasis]
M C Minvielle1, G Niedfeld, M L Ciarmela
1Cátedra de Microbiología y Parasitología, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina. jabasua@isis.unlp.edu.ar
Abstract:
The relationship between asthma and covert toxocariasis was studied in 38 patients with asthma and 44 control individuals (without asthma). Inclusion/exclusion criteria were determined. An ELISA test based on the detection of Anti-Toxocara canis (E/S antigen) serum immunoglobulin G (Ig G) and E (Ig E) was determined in both groups. Ordinary allergens and E/S antigen of T. canis injections were used to evaluate cutaneous reactivity. The seroprevalence in patients with asthma was 68.42%, and in the control individuals was 13.63%. This difference was significant. The percentage of asthmatic patients with two antitoxocara antibodies was 26.31% and 4.54% in control individuals. All asthmatic patients with antitoxocara IgE had cutaneous reactivity to Ag E/S. We conclude that the asthmatic patients with IgE and IgG antitoxocara suffer a covert toxocarosis.
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