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Updated: Sep 16, 2026

Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators
Published on: December 1, 2008
[Radioimmunoassay of substance P in human hypertrophic scar]
Objective:
To measure the content of substance P in human hypertrophic scar.
Method:
The method of radioimmunoassay was used to determine the content of substance P in human hypertrophic scar, non-hypertrophic scar and normal skin.
Result:
The content of substance P in hypertrophic scar was significantly higher than that in non-hypertrophic scar and normal skin (P < 0.01).
Conclusion:
Substance P may play an important role in the process of hypertrophic scar development.
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