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Pax 6: mastering eye morphogenesis and eye evolution
1Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland. gehring@ubaclu.unibas.ch
Trends in Genetics : TIG
|August 26, 1999
Abstract:
Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.