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Extrapyramidal type rigidity in rheumatoid arthritis.

S Ertan¹, I Fresko, H Apaydin

¹Department of Neurology, Cerrahpaşa Medical Faculty, University of Istanbul, Turkey.

Rheumatology (Oxford, England)

|August 26, 1999

Summary

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Rigidity, including cogwheeling, is present in about a quarter of rheumatoid arthritis (RA) patients, warranting further investigation. The study also explored the overlap between RA and Parkinson

Area of Science:

Rheumatology
Neurology
Clinical Research

Background:

Cogwheel rigidity was anecdotally observed in rheumatoid arthritis (RA) patients.
The clinical significance and prevalence of rigidity in RA require formal investigation.

Purpose of the Study:

To investigate the presence and frequency of rigidity and cogwheeling in patients diagnosed with RA.
To assess the co-occurrence of RA and Parkinson's disease (PD).

Main Methods:

A study cohort included 87 RA patients, 78 PD patients, and 67 healthy controls from a headache clinic.
Rigidity was assessed in all patient groups.

Main Results:

Rigidity was detected in 24% of RA patients, significantly more than in headache patients (2%; P = 0.00009).

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Parkinson's disease (PD) was diagnosed in 2.3% of RA patients, and RA was found in 7.7% of PD patients.

Conclusions:

Rigidity is a notable finding in approximately 25% of RA patients.
The study highlights a potential link and co-existence between rheumatoid arthritis and Parkinson's disease.