Related Experiment Videos
[Papular-purpuric gloves and socks syndrome].
R Feldmann1, M Harms, J H Saurat
1Dermatologische Abteilung, Krankenhaus der Stadt Wien-Lainz.
Summary
The papular-purpuric gloves and socks syndrome (PPGSS) presents with itchy, swollen hands and feet, oral lesions, and fever. Parvovirus B19 infection is a common cause, with other viruses occasionally implicated.
Area of Science:
- Dermatology
- Infectious Diseases
- Virology
Background:
- The papular-purpuric gloves and socks syndrome (PPGSS) was first described in 1990.
- PPGSS is a distinct clinical presentation characterized by specific skin and mucosal findings.
Observation:
- The syndrome involves itching, erythema, and edema of the hands and feet.
- Oral mucosal lesions and fever are commonly observed alongside the skin manifestations.
- Skin lesions progress to a purpuric stage and typically resolve spontaneously within days.
Findings:
- Acute parvovirus B19 infection is identified in over half of PPGSS cases.
- Other viral agents, including hepatitis B and measles, have been implicated in a minority of instances.
- This report details a specific patient case and provides a literature review.
Implications:
- Understanding the etiology of PPGSS aids in differential diagnosis.
- Identifying parvovirus B19 as a primary cause informs clinical management and prognosis.
- Further research into less common viral triggers may reveal additional pathogenic links.