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2-5A-PNA complexes: a novel class of antisense compounds
J C Verheijen1, S F Bayly, M R Player
1Leiden Institute of Chemistry, The Netherlands.
Nucleosides & Nucleotides
|September 4, 1999
Abstract:
This paper presents the fully automated solid phase synthesis of 2-5A-PNA hybrids. These stable antisense probes cause RNase L mediated hydrolysis of target RNA sequences.