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Optic disc edema in neonatal onset multisystem inflammatory disease (NOMID)
1Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Summary
Neonatal onset multisystem inflammatory disease (NOMID) is a rare condition affecting children. Optic disc edema can be a key sign differentiating NOMID from juvenile rheumatoid arthritis.
Area of Science:
- Ophthalmology
- Pediatrics
- Rheumatology
Background:
- Neonatal onset multisystem inflammatory disease (NOMID) is a rare autoinflammatory disorder.
- NOMID presents with a triad of neonatal rash, chronic meningitis, and recurrent fever, often leading to significant morbidity.
- Ophthalmologic manifestations are common but can be overlooked.
Observation:
- This report details a case of NOMID in a 28-month-old child.
- The child presented with characteristic neonatal rash, arthropathy, and central nervous system involvement.
- Optic disc edema was a notable ophthalmologic finding in this patient.
Findings:
- The diagnosis of NOMID was confirmed in the presented case.
- Optic disc edema was identified as a significant clinical sign.
- The case highlights the importance of recognizing ocular findings in NOMID.
Implications:
- Identifying optic disc edema or posterior uveitis in children with juvenile arthritis can aid in diagnosing NOMID.
- Early differentiation of NOMID from juvenile rheumatoid arthritis is crucial for appropriate management and improved outcomes.
- This case underscores the need for ophthalmologic evaluation in suspected NOMID cases.