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[Pulmonary carcinoids. Analysis of 53 cases]
V Beltrami1, L S Gallinaro, M Bezzi
1Dipartimento di Scienze Chirurgiche e Tecnologie Mediche Applicate, Università degli Studi di Roma La Sapienza.
Chirurgia Italiana
|October 9, 1999
Summary
This study analyzed 53 bronchial carcinoid tumors, finding atypical carcinoids more aggressive. Accurate histopathological classification is crucial for guiding treatment and prognosis in lung cancer patients.
Area of Science:
- Pulmonology
- Oncology
- Pathology
Background:
- Bronchial carcinoids are rare neuroendocrine tumors of the lung.
- Distinguishing between typical and atypical carcinoids is essential for patient management.
Purpose of the Study:
- To evaluate the clinical characteristics, treatment, and outcomes of bronchial carcinoid tumors.
- To emphasize the importance of histopathological classification for therapeutic and prognostic decisions.
Main Methods:
- Retrospective analysis of 53 bronchial carcinoid resections from a single institution.
- Histopathological examination to classify tumors as typical or atypical carcinoids.
- Median follow-up of 4.56 years to assess patient outcomes.
Main Results:
- The male/female ratio was 1:1.2, with a mean age of 52.2 years.
- 83% of tumors were typical carcinoids, and 17% were atypical carcinoids.
- One patient with atypical carcinoid experienced relapse and mortality; another developed a second primary lung cancer.
Conclusions:
- Histopathological classification is vital for accurate prognosis and therapeutic strategies in bronchial carcinoid cases.
- Atypical carcinoids exhibit higher aggressiveness, warranting treatment approaches similar to bronchogenic carcinoma.
- Surgical resection is a primary treatment modality with no intraoperative mortality observed in this cohort.