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Congenital subependymal giant-cell astrocytoma: case report with prenatal ultrasonogram
L D Mirkin1, E H Ey, M Chaparro
1Departments of Pathology and Pediatrics, Wright State University School of Medicine, Division of Pathology and Clinical Laboratory, One Children's Plaza, Dayton, OH 45404-1815, USA.
Background:
A prenatal sonogram at 27 weeks of gestation revealed a brain mass along the frontal horn and body of the lateral ventricle near the foramen of Monro in the fetus.
Materials And Methods:
A huge subependymal giant-cell astrocytoma was nearly totally resected at 11 days of age.
Results:
There was no syndromic family history, but features substantiating the diagnosis of tuberous sclerosis were recognized at 4 years of age.
Conclusion:
The sonographic finding of a tumor in the region of the foramen of Monro should raise the suspicion of a subependymal giant-cell astrocytoma, a tumor characteristically associated with tuberous sclerosis.
