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[Indications for vocal cord augmentation with collagen].
T Hacki1, R Böckler, J C Pérez Alvarez
1Abt. Phoniatrie und Pädaudiologie, Universitäts-Hals-Nasen-Ohren-Klinik Regensburg.
Laryngo- Rhino- Otologie
|October 27, 1999
Summary
Collagen vocal fold augmentation offers temporary glottic closure improvement for specific patient groups. This method is effective for vocal fold paralysis during neural regeneration or for patients with poor health.
Area of Science:
- Otolaryngology
- Regenerative Medicine
Context:
- Indirect laryngoscopic injection for vocal fold augmentation is less common than external medialization.
- Collagen augmentation remains clinically relevant for temporary glottic insufficiency treatment.
- Varied collagen elimination times allow tailored therapeutic strategies.
Purpose:
- To evaluate the efficacy of collagen compounds (Zyderm I, II, Zyplast) for vocal fold augmentation via indirect laryngoscopy.
- To determine the suitability of collagen augmentation for patients with neurogenic glottic insufficiency and vocal fold atrophy.
Summary:
- Thirty-seven patients with neurogenic glottic insufficiency and two with vocal fold atrophy received collagen injections.
- Compound selection was based on individual patient factors and condition severity.
- Significant improvement in glottic closure was observed in 33 patients; 6 showed minimal change.
Impact:
- Collagen augmentation provides temporary vocal fold medialization.
- It is a viable treatment for vocal fold paralysis during the neural regeneration phase.
- This technique is appropriate for patients with compromised health or limited life expectancy.