[Usefulness of visualized highly sensitive new chemical dosimeter: application to blood irradiation]

¹Department of Radiology, Jikei University School of Medicine.

Nihon Igaku Hoshasen Gakkai Zasshi. Nippon Acta Radiologica

|October 28, 1999

Abstract:

In the prophylaxis of post-transfusion GVHD, it is recommended to irradiate blood components with an absorbed dose ranging from 15 Gy to 50 Gy. We applied a new chemical dosimeter to measure absorbed dose for blood irradiation. This system is composed of diphenyliodoniumchloride (DICI) as an oxidizer and crystal violet lactone as a pH indicator. Protons are released from DICI after irradiation. The maximum absorption wavelength of this indicator is 610 nm, and absorbance is linearly related with a given dose from 1 to 50 Gy. Coloration is stable for at least 2 weeks when stored in the dark at 4 degrees C. This system may be used as a chemical dosimeter for blood irradiation.

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Abstract:

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