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Obstructive nephropathy due to sulfa crystals in two HIV seropositive patients treated with sulfadiazine
R Colebunders1, K Depraetere, E De Droogh
1Institute of Tropical Medicine, Department of Clinical Sciences, Antwerp, Belgium.
Abstract:
Two HIV seropositive patients receiving sulfadiazine for presumed cerebral toxoplasmosis who developed an obstructive nephropathy are described. Ultrasound examination showed respectively a bilateral hydro-ureteronephrosis in one patient and unilateral hydro-ureteronephrosis in the other. The obstructive nephropathy resolved in both patients with alkalic hydration and discontinuation of the sulfadiazine.