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A comparison of the preventive effects of lanthanides and fluoride on human experimental root surface carious-like
1Department of Oral Pathology, School of Stomatology, Shanghai Second Medical University (SSMU), P. R. China.
Objective:
To investigate the mechanisms of lanthanides prevention of human root surface carious-like lesions and to compare the effectiveness of lanthanum (La) with that of cerium (Ce) and fluoride (F). Various treatment procedures were also compared.
Materials And Methods:
Acetic buffers containing lanthanum, cerium, and fluoride (500 ppm) were used individually or in combination to treat 48 cementum-dentin samples. The acid-resistant capacity of various treatment procedures was evaluated by means of scanning electron microscope, electron microprobe, and polarizing light microscope analyses.
Results:
The acid-resistant effects of lanthanide element were comparable to those of fluoride, and their acid-resistant effects were even stronger when combined with fluoride and cerium. These effects are likely due to the formation of La(Ce)HAP, FLa(Ce)HAP, and lanthanum/cerium phosphate compounds.
Conclusion:
Combined F/La(Ce) was more effective in the prevention of root surface caries than were lanthanides alone.