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Infantile colic and small intestinal function: a nutritional problem?

T Lindberg1

  • 1Department of Experimental Research, Malmö University Hospital, University of Lund, Sweden.

Acta Paediatrica (Oslo, Norway : 1992). Supplement
|November 24, 1999
PubMed
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About 25% of infants with colic have cow's milk-dependent colic. Dietary changes, like a cow's milk-free diet for mothers or casein-hydrolysate formula, can resolve colic and prevent future food allergies.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Allergy

Background:

  • Infant colic affects a significant number of infants, characterized by excessive crying.
  • A subset of these infants exhibits colic directly related to cow's milk consumption.
  • Abnormal intestinal function is suspected in colicky infants, but its exact nature remains unclear.

Purpose of the Study:

  • To identify the prevalence of cow's milk-dependent colic in infants.
  • To propose dietary management strategies for cow's milk-dependent colic.
  • To explore potential indicators of abnormal intestinal function in colicky infants.

Main Methods:

  • Observational analysis of infant colic cases.
  • Dietary intervention recommendations for breastfed and formula-fed infants.

Related Experiment Videos

  • Review of physiological markers associated with intestinal function.
  • Main Results:

    • Approximately 25% of infants with moderate to severe colic are dependent on cow's milk.
    • A strict cow's milk-free maternal diet or casein-hydrolysate formula is recommended.
    • Several signs suggest abnormal intestinal function in colicky infants, including increased macromolecular absorption and altered gut hormone levels.

    Conclusions:

    • Cow's milk is a significant trigger for colic in a quarter of affected infants.
    • Dietary modifications are effective in managing cow's milk-dependent colic without nutritional compromise.
    • Further research is needed to elucidate the underlying intestinal abnormalities in infantile colic.