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Gd(3+)-loaded polyion complex for pH depiction with magnetic resonance imaging
M Mikawa1, N Miwa, M Bräutigam
1Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan.
Journal of Biomedical Materials Research
|December 22, 1999
Summary
Researchers developed a novel pH-responsive MRI contrast agent using polyion complexes. This gadolinium-based agent shows significant changes in MRI signal intensity with pH variations, enhancing diagnostic potential.
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