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[Lipoprotein (a) and the evaluation of low density cholesterol by the Friedewald formula: a new problem for an old
C Hernández1, P Chacón, L García-Pascual
1Sección de Endocrinología, Hospital General Universitari Vall d'Hebron, Barcelona.
Medicina Clinica
|December 22, 1999
Abstract
Background:
To evaluate the influence of lipoprotein(a) [Lp(a)] concentration on the LDL-cholesterol calculated by the Friedewald formula.
Material And Methods:
Lp(a) was determined to a worker population of 947 subject in order to perform a correction of LDL-cholesterol obtained by the Friedewald formula.
Results:
In subjects in whom Lp(a) was > 30 mg/dl (12.9%) LDL-cholesterol levels were overestimated 10 mg/dl at least.
Conclusion:
Lp(a) should be considered in order to reduce Friedewald's formula error on the estimation of LDL-cholesterol.