Related Experiment Video
Updated: Feb 7, 2026
09:49
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
3.8K
Brain abscesses from neglected open head injuries: experience with 17 cases over 20 years
1Regional Hospital of Sion, Switzerland.
Swiss Surgery = Schweizer Chirurgie = Chirurgie Suisse = Chirurgia Svizzera
|December 23, 1999
Summary
This study reviews 17 post-traumatic brain abscess cases. Early surgical excision after aspiration is a highly effective treatment for brain abscesses, especially those caused by fractures.
Area of Science:
- Neurosurgery
- Infectious Diseases
Background:
- Post-traumatic brain abscesses are serious intracranial complications.
- Neglected compound depressed fractures are a primary cause of these abscesses.
Observation:
- A review of 17 civilian cases over 20 years treated with CT scanning.
- One case involved a newborn with a parietal abscess due to vacuum extraction.
Findings:
- Treatment methods included aspiration and surgical excision (craniotomy).
- Early subsequent excision (2-3 days post-aspiration) yielded satisfactory results with no deaths in 7 cases.
- Primary excision had a higher mortality rate (1 death in 4 cases).
- Bone fragments in the abscess cavity necessitate excision.
- Commonly cultured bacteria included mixed flora (streptococci, staphylococci) and Staphylococcus aureus.
Implications:
- Early surgical intervention, particularly excision, is crucial for managing post-traumatic brain abscesses.
- Antibiotics are vital adjuncts in treatment.
- CT scanning aids in diagnosis and management planning.
Related Concept Videos
01:19Muscles that Move the Head
6.0K
The muscles that move the head are a dynamic and complex group of structures that work together to facilitate a wide range of head movements, including rotation, flexion, extension, and lateral bending.
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
6.0K
01:12What is an Experiment?
18.9K
An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
18.9K
01:19Thomson's e/m Experiment
6.9K
In a beam of charged particles created by a heated cathode, the particles move at different speeds. However, many applications need a beam with uniform particle speeds. An arrangement known as a velocity selector uses electric and magnetic fields to pick particles with a particular speed from the beam.
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
6.9K
01:13Controls in Experiments
17.7K
When conducting an experiment, it is crucial to have control to reduce bias and accurately measure the dependent variables. It also marks the results more reliable. Controls are elements in an experiment that have the same characteristics as the treatment groups but are not affected by the independent variable. By sorting these data into control and experimental conditions, the relationship between the dependent and independent variables can be drawn. A randomized experiment always includes a...
17.7K
01:13Randomized Experiments
9.1K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
9.1K
01:16Crossover Experiments
4.6K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
4.6K