[Sebaceous hyperplasia of the lower eyelid]

A 61-year-old man was evaluated for a yellow tumor located at the lid margin of his lower eyelid, which had recurred for the second time after surgical excision. The patient's ocular examination was otherwise unremarkable as was the general examination with the exception of the presence of a polyp in the colon and a family history of multiple colorectal carcinomas. The eyelid tumor was excised and histologic examination showed a sebaceous hyperplasia.

When one encounters a sebaceous tumor involving the eyelid the possibility of Muir-Torre syndrome should be considered. Muir-Torre syndrome is an autosomal dominant genodermatosis characterized by at least a single sebaceous gland tumor (either a hyperplasia, an adenoma, an epithelioma, or a carcinoma) and a minimum of one internal malignancy.