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Updated: Aug 14, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
[Role of 99mTC-Sestamibi in the diagnosis of breast cancer. Report on 100 cases]
M V Fliquete Peris1, J Giménez Climent, C Vázquez Forner
1Servicio de Medicina Nuclear, Fundación Intituto Valenciano de Oncología (IVO), Valencia, 46009, España.
Objective:
To evaluate the usefulness of the isotopic mammography with 99mTc-MIBI in the diagnosis of tumoral pathology of the mammary gland.
Methods:
One hundred women with clinical/radiological suspicion of malignant pathology in the breast and/or lymph nodes were studied. The isotopic technique consisted of administration 740MBq 99mTc-MIBI, i.v., obtaining AP and prone lateral views.
Results:
The overall sensitivity and specificity for the scintimammography in tumoral detection was 90% and 86% respectively. The sensitivity was 60% in nonpalpable lesions. The scintimammography had a 40% sensitivity and 98% specificity in lymph node detection.
Conclusion:
The complementary use of scintimammography can improve the sensitivity for the detection of breast carcinoma. The diagnostic accuracy of 99mTc-MIBI depends on the tumor size and histopathological characteristics. The 99mTc-MIBI can potentially determine the presence of recurrent breast cancer and multicentric disease.
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