Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sclerochoroidal calcification associated with Gitelman syndrome.

T Bourcier1, P Blain, P Massin

  • 1Department of Ophthalmology, Hôpital Lariboisière, Universitè Paris 7, France.

American Journal of Ophthalmology
|December 28, 1999
PubMed
Summary

Gitelman syndrome, a genetic disorder, may cause sclerochoroidal calcification. This study reports a case of bilateral subretinal lesions consistent with calcium deposits in a patient with this condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unlocking stray light mysteries in the CoRot baffle with the time-of-flight method.

Scientific reports·2024
Same author

Bilateral cystoid maculopathy as first manifestation of SARS-CoV-2 infection.

Journal francais d'ophtalmologie·2021
Same author

The Far Ultra-Violet imager on the ICON mission.

Space science reviews·2021
Same author

[Epiretinal membranes].

Journal francais d'ophtalmologie·2015
Same author

[Current uses and indications for indocyanine green angiography].

Journal francais d'ophtalmologie·2011
Same author

[Unusual retinal abnormality: retinal hemorrhages related to scurvy].

Journal francais d'ophtalmologie·2011

Area of Science:

  • Ophthalmology
  • Medical Genetics
  • Nephrology

Background:

  • Gitelman syndrome is an autosomal recessive renal tubular disorder characterized by hypokalemia, hypomagnesemia, and metabolic alkalosis.
  • Ocular manifestations of Gitelman syndrome are rare, with limited documented cases.

Observation:

  • A 58-year-old woman with a history of Gitelman syndrome presented with bilateral, symmetric yellow-white subretinal lesions in the superotemporal midperiphery.
  • Fundus examination revealed abnormalities consistent with calcium deposition upon tomodensitometry.

Findings:

  • The observed sclerochoroidal calcification is hypothesized to be a consequence of chronic and severe hypomagnesemia associated with Gitelman syndrome.
  • This case highlights a potential, previously under-recognized ocular complication linked to this genetic condition.

Related Experiment Videos

Implications:

  • Gitelman syndrome should be considered in the differential diagnosis of patients presenting with unexplained sclerochoroidal calcification.
  • Further research is warranted to elucidate the precise mechanisms linking hypomagnesemia in Gitelman syndrome to ocular calcification.