Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Customised compensation using intensity modulated beams delivered by dynamic multileaf collimation.

J H Mott1, A R Hounsell, G J Budgell

  • 1North Western Medical Physics, Christie Hospital NHS Trust, Withington, Manchester, UK.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|January 7, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel Quantum Spin Liquid States in the S=1/2 Three-Dimensional Compound Y_{3}Cu_{2}Sb_{3}O_{14}.

Physical review letters·2026
Same author

Risk of Revision and Patient-Reported Outcomes Following Primary UKR Performed Using Computer Navigation or Patient-Specific Instrumentation: An Analysis of National Joint Registry Data.

The Journal of bone and joint surgery. American volume·2025
Same author

The Effects of Computer Navigation and Patient-Specific Instrumentation on Risk of Revision, PROMs, and Mortality Following Primary TKR: An Analysis of National Joint Registry Data.

The Journal of bone and joint surgery. American volume·2025
Same author

The Risk of Postoperative Periprosthetic Femoral Fracture After Total Hip Arthroplasty Depends More on Stem Design Than Cement Use: An Analysis of National Health Data from England.

The Journal of bone and joint surgery. American volume·2025
Same author

Performance evaluation of an inorganic optical fibre dosimeter for use in external beam radiotherapy with pulsed beams.

Physics in medicine and biology·2024
Same author

The Association of Incidental Radiation Dose to the Heart Base with Overall Survival and Cardiac Events after Curative-intent Radiotherapy for Non-small Cell Lung Cancer: Results from the NI-HEART Study.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023

Customised compensation using intensity modulated radiation therapy (IMRT) and a dynamic multileaf collimator (MLC) improves dose homogeneity for pelvic region treatments. This simple IMRT technique aids in implementing advanced 3D conformal therapy.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Technology

Background:

  • Intensity modulated radiation therapy (IMRT) is crucial for precise radiation delivery.
  • Pelvic region treatments require high dose homogeneity for efficacy and reduced side effects.
  • Dynamic multileaf collimator (MLC) application enables advanced radiotherapy techniques.

Purpose of the Study:

  • To develop and evaluate customised compensation for IMRT in pelvic treatments.
  • To improve dose homogeneity using dynamic MLC application.
  • To facilitate the clinical implementation of complex 3D conformal therapy.

Main Methods:

  • Computer software generated intensity modulated beam profiles for uniform dose distribution.
  • Interpreter software determined MLC leaf trajectories for a unidirectional sweep.

Related Experiment Videos

  • Dose calculations and fine adjustments were performed based on calculated leaf positions.
  • Main Results:

    • The compensation procedure was successfully tested using film dosimetry.
    • Dose distributions were investigated in an anthropomorphic phantom.
    • Overall dose homogeneity was significantly improved.

    Conclusions:

    • Customised compensation via dynamic MLC is effective in enhancing dose homogeneity.
    • This IMRT approach simplifies the delivery of complex radiotherapy.
    • The method shows promise for improved pelvic treatment outcomes.