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Synthesis and antimicrobial activity of bis[6-phenyl-4-methyl-3-substituted-pyrazo[4,5-d] pyrazol-1-yl]thioketones
M S Chande1, N V Thakkar, D V Patil
1Department of Chemistry, Institute of Science, Mumbai, India.
Acta Poloniae Pharmaceutica
|January 15, 2000
Abstract:
New bis[6-phenyl-4-methyl-3-substituted-pyrazo[4,5-d] pyrazol-1-yl]thioketones have been obtained in good yield by the reaction of thiocarbohydrazine with 1-phenyl-3-methyl-4-acetyl/benzoyl-pyrazol-5-one, followed by cyclization of the intermediate. The new compounds exhibit excellent antimicrobial activity.