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The breast cancer gene database: a collaborative information resource
R A Baasiri1, S R Glasser, D L Steffen
1Department of Cell Biology, Baylor College of Medicine, Houston, Texas, TX 77030, USA.
Oncogene
|January 19, 2000
Summary
The Breast Cancer Gene Database (BCGD) compiles crucial molecular genetic data on breast cancer genes from research literature. This freely accessible online resource aids researchers in understanding gene roles in oncogenesis.
Area of Science:
- Bioinformatics
- Molecular Biology
- Genetics
Background:
- Breast cancer research relies on comprehensive genetic data.
- Existing data sources may be fragmented or difficult to access.
Purpose of the Study:
- To create a centralized, accessible repository for breast cancer gene information.
- To facilitate research into the genetic basis of breast cancer.
Main Methods:
- Data extraction from published biomedical literature.
- Organization of data into gene-specific categories and 'Facts'.
- Development of web-based forms for data submission and retrieval.
Main Results:
- The Breast Cancer Gene Database (BCGD) is established and publicly available.
- The database allows searches by gene name or keywords.
- Data is linked to other major genetic resources like Entrez and GeneCards.
Conclusions:
- BCGD provides a valuable, continuously updated resource for breast cancer gene research.
- The platform supports collaborative authoring and worldwide accessibility.
- Facilitates rapid retrieval of gene characteristics, functions, and oncogenic roles.