[Stress can induce neuroendocrine disorders and pain]

In this article, a number of hormones and neuropeptides regulating pain, well-being and stress are shown to play important roles in the association between stress perception and nociception. Derangements in the stress axis may be induced by a variety of factors in which life events, personality, psychosocial circumstances and gender all may contribute. When such derangements are long-lasting, probably several neuroendocrine modifications are induced, giving rise to many of the symptoms seen in chronic pain syndromes including fibromyalgia.